Why DNA + Protein Single-cell Multi-omics?

Cancer is a complex disease with a mix of cells in varied states. Understanding the effect of genotype on immunophenotype at the single-cell level reveals disease processes and ultimately enables better therapies. A single-cell multi-omics approach is the only way to achieve full resolution of tumor heterogeneity. Perform true multi-omics with simultaneous detection of SNVs, CNVs, and cell-surface proteins at the single-cell level.

Correlate immunophenotype with genotype from the same cell.

Distinguish subclones from minimal residual disease with single-cell multi-omics based on SNVs, CNVs, and protein expression.

Eliminate inferences while saving on research budgets and analysis times.

Explore insights of single-cell multi-omics in myeloid malignancies

Explore insights of single-cell multi-omics in myeloid malignancies

Ross Levine, MD, Memorial Sloan Kettering Cancer Center

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The Tapestri Workflow

Integrate seamlessly into your existing NGS workflow with sample prep and analysis solutions using the Tapestri single-cell sequencing platform

With our single-cell sequencing platform, use the Tapestri Instrument, reagents, and consumables up-front of your NGS system and then Tapestri Pipeline and Tapestri Insights software for data analysis and visualization.

TARGET SELECTION

Choose a pre-designed or custom DNA panel

SAMPLE PREP

Add a protein panel and simple cell staining protocol

LIBRARY PREP

Single workflow combines DNA and protein panels

SEQUENCING

Single sequencing run for multi-omics single-cell data

PIPELINE

Integrated pipeline for multi-omics analysis

ANALYSIS

Powerful analysis and visualization software

Datasets

Explore the datasets below using single-cell multi-omics analysis.

NAME

DESCRIPTION

LAST UPDATED

Sample dataset for the Tapestri Single Cell DNA AML panel

12.22.2021

OTHER CAPABILITIES

DNA Is Our Foundation

Providing cancer specialists with the only single-cell targeted DNA solution that integrates SNV, CNV, and protein data from the same cell.

 Single-cell Genomics (DNA)

Single-cell Genomics (DNA)

SNV

Detect rare clonal populations and identify co-occurrence and zygosity.

SNV + CNV

Characterize genomic heterogeneity using a single comprehensive platform.

Ready to build your DNA + Protein panel?

Chat with one of our design experts to build a panel to simultaneously detect SNVs, CNVs, and protein expression.

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