Why Single Cell for SNVs and Indels?
The average readout from conventional bulk sequencing misses the underlying genetic diversity across cell populations. Single-cell DNA sequencing for single nucleotide variants and indels provides the true measure of clonal heterogeneity without inferring or guessing. Reveal the true clonal architecture in a tumor sample without the assumptions confounded by bulk sequencing.
Identify true mutation co-occurrence in clonal populations.
Detect rare subclones down to 0.1% that may be missed by bulk sequencing.
Determine the zygosity that matters for your disease research.
See how single-cell DNA sequencing reveals clonal evolution in AML patients on gilteritinib.
Cathy Smith, MD, University of California, San Francisco
The Tapestri Workflow
Integrate seamlessly into your existing NGS workflow with sample prep and analysis solutions using the Tapestri single-cell sequencing platform
With our single-cell sequencing platform, use the Tapestri Instrument, reagents, and consumables up-front of your NGS system and then Tapestri Pipeline and Tapestri Insights software for data analysis and visualization.
Target Selection
Choose a pre-designed or custom DNA panel
SEQUENCING
Single sequencing run for multi-omics single-cell data
Datasets
Explore the datasets below using single-cell DNA analysis for single nucleotide variants
NAME | DESCRIPTION | LAST UPDATED |
|---|---|---|
Sample dataset for the Tapestri Single Cell DNA AML panel | 12.22.2021 | |
Sample dataset for the Tapestri Single Cell DNA Myeloid panel | 12.22.2021 | |
Sample dataset for the Tapestri Single Cell DNA CLL panel | 12.22.2021 |
DNA Is Our Foundation
Providing cancer specialists with the only single-cell targeted DNA solution that integrates SNV, CNV, and protein data from the same cell.
Single-cell Genomics (DNA)
SNV + CNV
Characterize genomic heterogeneity using a single comprehensive platform.
Single-cell Multi-omics (DNA+)
DNA + Protein
Gain a true multi-omics picture from genotype to phenotype.
Ready to build a custom panel?
Use Tapestri Designer to design a custom panel tailored to your needs.