Why Single Cell for SNVs and CNVs?
When determining the clonal heterogeneity across a cancer sample, it’s important to comprehensively measure both DNA mutations and copy number variants in every cell to give us higher resolution to explore tumor evolution and heterogeneity. Gain unprecedented insight into the diversity of genomic changes with simultaneous SNV and CNV analysis from the same cell.
Obtain quality for your research with best-in-class single-cell DNA accessibility using the Tapestri two-step microfluidic workflow.
Use a single workflow for co-detection of gene-level to chromosome-level CNVs, LOH, and SNVs in single cells.
Start from cells or nuclei with maximum sample flexibility for CNV analysis.
Discover how single-cell SNV and CNV analysis helps better resolve the heterogeneity in renal cell carcinoma (RCC) samples.
Samra Turajlic, MD, Francis Crick Institute
The Tapestri Workflow
Integrate seamlessly into your existing NGS workflow with sample prep and analysis solutions using the Tapestri single-cell sequencing platform
With our single-cell sequencing platform, use the Tapestri Instrument, reagents, and consumables up-front of your NGS system and then Tapestri Pipeline and Tapestri Insights software for data analysis and visualization.
Target Selection
Choose a pre-designed or custom DNA panel
SEQUENCING
Single sequencing run for multi-omics single-cell data
Datasets
Explore the datasets below using single-cell SNV and CNV analysis
NAME | DESCRIPTION | LAST UPDATED |
|---|---|---|
Sample dataset for a 4-cell line mixed experiment using the Tapestri Single-Cell DNA AML_v2 panel | 12.22.2021 |
DNA Is Our Foundation
Providing cancer specialists with the only single-cell targeted DNA solution that integrates SNV, CNV, and protein data from the same cell.
Single-cell Genomics (DNA)
SNV
Detect rare clonal populations and identify co-occurrence and zygosity.
Single-cell Multi-omics (DNA+)
DNA + Protein
Gain a true multi-omics picture from genotype to phenotype.
Featured Resources
Simultaneous analysis of SNVs and CNVs in a single cell
Ready to build your SNV + CNV panel?
Chat with one of our design experts to build a panel to perform simultaneous SNV and CNV analysis.