Identifying copy number variations (CNV) in single cells for breast cancer research (Language: Mandarin)

Tapestri Solution for Solid Tumor Research provides the resolution required to profile thousands of individual cells or nuclei, enabling a much richer characterization of tumor heterogeneity and clonality. Some key takeaways from this application note include:

• Mission Bio’s Nuclei Extraction Protocol works effectively for fresh frozen breast cancer samples and can generate high-quality single-cell DNA data.

• Tapestri Single-cell DNA Breast Cancer Research Panel V2, validated by world class key opinion leaders, including our inaugural Center of Excellence for Solid Tumor.

• The Tapestri Platform, combined with the new Tapestri Single-cell CNV Analysis Tool, enables co-measurement of single-cell SNVs and CNVs across thousands of single cells.