Single-cell DNA analysis of myelodysplastic syndrome using the Tapestri Single-cell DNA AML Panel

Accumulation of genetic mutations can occur during clonal expansion of aberrant cells, leading to a heterogeneous mixture of affected cells that can change a patient’s prognosis. Clonal lineage reconstruction provides a more comprehensive picture of the disease progression. Distinguishing mutational status at the single-cell level offers precision in diagnosis and informs treatment options. Learn how the Tapestri Single-cell DNA AML Panel was used to examine 2 patients with myelodysplastic syndrome (MDS).